Bunnie XO describes suicidal ideation on a GLP-1
Podcast host Bunnie XO told People she had a bout of suicidal ideation while taking a GLP-1 drug, adding a rare mental-health account to the wave of celebrity weight-loss drug stories.[1]
Bunnie XO, the podcast host married to musician Jelly Roll, said in December 2025 that she experienced "a bout of suicidal ideation" while taking a GLP-1 medication, according to an interview with People.[1] The report does not name the specific drug she was using.[1]
Bunnie XO described the experience as one of the darkest stretches of her life. "I prided myself on the fact that I only had anxiety," she said. "I never had depression. So when you get slammed with suicidal ideation and visions and just, oh, it was horrific."[1] She said she turned to a GLP-1 because of a family history of diabetes. "Both my parents had diabetes. So my insulin numbers are really crazy and my body just cannot tolerate it," she told People.[1] She called that December a "rough month" and said she is "good now."[1]
Her account appeared in a roundup of celebrities who have talked publicly about GLP-1 medications, most of whom described weight loss, blood sugar improvement, or physical relief. Serena Williams said her blood sugar and joints improved after starting a GLP-1 following the birth of her second child.[1] Eric Stonestreet said Mounjaro was "a game changer" for his Type 2 diabetes.[1] Chrissy Teigen said she used Ozempic after a 2020 miscarriage and struggled with reduced hunger cues.[1] Against that backdrop, Bunnie XO's description of suicidal ideation stands out as one of the more negative personal accounts to surface from a high-profile figure.[1]
The source material does not include clinical data on how common suicidal ideation is among GLP-1 users, nor does it cite any statement from Novo Nordisk or Eli Lilly about her case. It also does not specify whether she was diagnosed with diabetes, prediabetes, or was using the drug for another reason, beyond her comment about family history and insulin numbers.[1]
Why it matters for patients
GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound are widely used for diabetes and weight management, and most public accounts collected in this report describe positive results, including weight loss and improved blood work.[1] Bunnie XO's story is notable because mental health side effects are discussed far less often than physical ones like nausea or appetite changes in these celebrity accounts.[1]
Her account is one person's experience, not a study, and the source does not say whether her symptoms were confirmed to be linked to the medication itself, to her underlying health situation, or to other factors.[1] Readers weighing their own experience with a GLP-1, or supporting a family member who is, may find it useful to know that both positive and negative psychological experiences have been described publicly by different people taking these drugs, and that individual reactions can vary.[1]
What is not known from this source is any accompanying medical or regulatory response, whether Bunnie XO is still taking a GLP-1, or how her experience compares with formal safety monitoring data, since none of that information appears in the report.[1]
What happens next
The available reporting does not include a specific date for further updates, additional medical detail from Bunnie XO, or any response from drugmakers regarding her account.[1] No new milestones are described in the source material.[1]
Sources
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