What do you want to know about GLP‑1 medications?
Sourced answers about Ozempic, Wegovy, Mounjaro, Zepbound and newer pills, written for people not prescribers.
Do I qualify?Wegovy vs ZepboundIs compounded semaglutide legal?Can I drink alcohol?What happens when I stop?
Pick your medication
The most-asked questions
See the full FAQCostHow Much Does Semaglutide Cost Without Insurance in 2026?Without insurance, brand-name semaglutide now runs about $149 to $499 a month depending on which product and dose you take, far below the $1,027 to $1,349 list prices.Side effectsHow to Stop Nausea from Semaglutide: Timing, Diet, and Warning SignsNausea on semaglutide is common, peaks during the first 4 to 5 weeks and during dose escalation, and usually resolves within 8 days. Slower eating, smaller low-fat meals, and small sips of fluid help; a prescriber can slow the dose schedule if needed.Getting startedDo I Qualify for Wegovy, Zepbound or Another GLP-1, and Who Decides?There is no application and no official qualification body. Three separate gates decide access: the FDA label, a prescriber's judgment, and your insurance plan. The weight-loss labels cover adults with obesity, or overweight plus at least one weight-related condition — and print no BMI number.Stopping and switchingWhat Happens When You Stop Taking a GLP-1?Stopping a GLP-1 usually leads to substantial weight regain within a year. In a pooled analysis of 8,993 adults across 6 studies, the difference in percent body-weight change between people who stopped and people who continued averaged 17.90%.CompoundedIs Compounded Semaglutide Legal in 2026? What the FDA Rules SayCompounded semaglutide is not banned by name, but mass compounding of copies ended after FDA resolved the shortage on February 21, 2025. Enforcement-discretion windows closed April 22, 2025 (503A) and May 22, 2025 (503B), and FDA now says semaglutide is on neither the shortage list nor the 503B bulks list.Side effectsCan You Drink Alcohol on Semaglutide? What Labels and Trials SayThe Ozempic and Wegovy labels list contraindications for MTC/MEN 2 and hypersensitivity, and interactions with insulin and oral drugs. In a 26-week trial, semaglutide cut heavy drinking days by 41.1 vs 26.4 percentage points.
This week in GLP‑1 news
News timeline back to 2017- Research and trials
Orforglipron matches insulin glargine on cardiovascular safety in ACHIEVE-4
- Research and trials
CVS Caremark adds Zepbound back to commercial formularies starting October 1
Browse all 218 guides
AlternativesResultsCompoundedMedicationsDrug pipelineSide effectsHow to useGLP-1 cultureCostStopping and switchingFDA and regulationGetting startedThe drugmakersFoundayoLiraglutideWho they're forCommon questionsInsuranceThe GLP-1 marketHow it worksTrial evidenceEmerging usesOzempicWegovyMounjaroZepboundSemaglutideTirzepatide