Tracy Morgan says Ozempic is behind his weight loss

Tracy Morgan says his weight loss came from Ozempic. Appearing on TODAY with Hoda & Jenna, he said, "That's Ozempic. That's how this weight got lost," and turned the admission into a punchline ^[1]. He has since joked that he had "out-eaten Ozempic" and gained 40 pounds ^[1].

Ozempic is approved to treat Type 2 diabetes, and weight loss is a prominent side effect, so the drug is often prescribed off-label for weight loss ^[1]. Its active ingredient, semaglutide, is also approved to treat obesity under the brand name Wegovy ^[1]. Novo Nordisk, the maker of Ozempic, has said it does not support off-label use of its medications ^[1]. Similar drugs include Mounjaro, approved for diabetes, and Zepbound, approved for obesity; both are tirzepatide and made by Eli Lilly ^[1].

Morgan's disclosure places him among a small group of public figures who have put a drug name to a visible weight change, at a time when the public has been openly curious about which celebrities are using these medications ^[1]. Some of those accounts include specific numbers:

• Renee Graziano of "Mob Wives" said she lost 52 pounds using Mounjaro as of May 2025 ^[1].
• Savannah Chrisley said she stopped one weight-loss drug because it blunted her appetite, then lost 25 pounds on tirzepatide ^[1].
• Eric Stonestreet said he has taken Mounjaro for Type 2 diabetes since it came out in May 2022 ^[1].
• Rosie O'Donnell said in August 2025 that she is a size 12 and credited Mounjaro ^[1].

The experiences described publicly are not all positive. Bunnie XO said in December 2025 that she had "a bout of suicidal ideation" while taking a GLP-1, and described that period as one of the darkest of her life ^[1]. Chrissy Teigen said she turned to Ozempic after a 2020 miscarriage, at a point when she had gained about 40 pounds during a pregnancy she lost at 20 weeks, and she said the drop in hunger cues was frustrating for her ^[1].

Why it matters for patients

Ozempic and Wegovy are the same molecule under different brand names, but they carry different FDA approvals — one for Type 2 diabetes, one for obesity ^[1]. That difference can shape which version a clinician writes and how a plan covers it. A celebrity saying "Ozempic" does not tell a patient which of the two was prescribed, at what dose, or for which diagnosis.

Morgan has not said whether he has diabetes or was prescribed the drug for weight loss, and it has not been reported whether he still takes semaglutide ^[1]. That is the same gap that runs through most of these disclosures: several celebrities in TODAY's reporting said they used a drug without naming it, including Oprah Winfrey, who said she uses a weight-loss drug "as I feel I need it," and Kelly Clarkson, who said hers is "not" Ozempic ^[1].

Reported side effects also range widely across these accounts, from people who call the drugs a "game changer" to one who described suicidal ideation ^[1]. TODAY's report includes the note that anyone interested in trying a weight-loss medication should speak with a doctor first ^[1].

Celebrity coverage can also feed demand and confusion at once: the article notes that as these drugs grew in popularity, part of the interest was members of the public trying to guess which celebrities were on them ^[1]. What a famous person says on a talk show is not the same as what a prescription label says.

What is not known

It has not been disclosed whether Morgan was taking Ozempic or Wegovy, what dose he used, or whether he was being treated for diabetes or for weight loss ^[1]. It also has not been reported whether he is still taking semaglutide or has stopped ^[1].